Document Type : Articles
Authors
Food Science Department, College of Agriculture, Tikrit University, Tikrit, Iraq
Abstract
This study was designed to determine the effect of Actimel milk on the weights of rats and the level of Total cholesterol (TC), Triglycerides (TG), High density lipoprotein cholesterol (HDL-C), Low density lipoprotein cholesterol (LDL-C), Very low density lipoprotein cholesterol (VLDL- C), and the effectiveness of liver enzymes ALT, AST, and ALP in healthy adult male Sprague-Dawley rats suffering from hypercholesterolemia as an experimental model for this study. The rats were distributed into four groups (six rats each): the healthy control (T1), the infected control (T2), the infected and treated with yogurt milk (T3), and the infected and treated with Actimel milk (T4). After the end of the milk feeding period (28 days), the results showed a significant decrease (p<0.05) in the weight of the rats and the levels of TC, TG, LDL-C, and VLDL-V, and a significant increase in the HDL-C values of the rats fed the milk of the groups (T3, T4) compared with the infected control group (T2). As for the activity of liver enzymes ALT, AST, and ALP, the largest decrease was in the (T4) group compared to the infected control group (T2). It can be concluded that Actimel milk played a positive role in improving the blood lipid profile in rats suffering from hypercholesterolemia.
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