Document Type : Articles
Authors
1 Education Directorate Salah Al-deen, Ministry of Education, Iraq
2 Food Science Department, College of Agriculture, Tikrit University, Iraq
Abstract
The current study was designed to observe and test the effect of the Wheatgrass aqueous extract on blood parameters and histological changes in liver and kidneys in male albino mice that were exposed to aluminum poisoning (40 mg/kg bw) for 30 days. The animals were divided into (3) groups containing five (5) animals and weighing (20-24 gm). The results of oral administration with aluminum showed a significant decrease in final body weight and the weight of the liver, spleen and testes. And concentrations of each of the RBCs, HCB, HCT, MCV, MCH, MCHC and GRAN. And a significant increase in WBC, LYM and MON. The weight of the kidneys and heart were not significantly different compared to the healthy control group. A microscopic examination of liver and kidney tissue sections of the group of animals treated with aluminum observed central vein congestion (CON), separation of the central wall vein and part of it in the liver Picture. In the kidneys Picture shows the degeneration of most urinary tubule cells (D) with clear hemorrhage within the kidney tissue. The results of the treatment with wheatgrass + aluminum had a positive effect on body weight, organs, and blood parameters. And observed the normal shape of the central vein (CV), hepatic cells (HC) and hematopoietic sinuses in the liver Picture, showing the semi-normal shape of urinary tubules (UT) and renal glomeruli (G) with hemorrhage (H) within the kidney tissue Picture, compared with the aluminum infected group. Therefore, it can be concluded that wheatgrass has a great ability to improve hematological parameters and histological changes in the liver and kidneys.
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