Document Type : Articles
Authors
1 1Department of Biology, Education College for Women, University Of Anbar, Ramadi, Iraq
2 Department of Biology, College of Science, University Of Anbar, Ramadi, Iraq
3 Department of Biology, Education College for Women, University Of Anbar, Ramadi, Iraq
Abstract
This study aimed to investigate the effects of mycotoxins, specifically aflatoxin B1, and various bioadsorbents (yeast, zeolite, vitamin E) on the male reproductive system of rats by evaluating their impact on the levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone. The experiment was conducted with 36 adult male rats, weighing between 60-180 grams. The rats were randomly divided into six groups, each with six replicates. The groups were: T1, the control group with no additives; T2, addition of 0.5 ml of aflatoxin B1; T3, addition of 0.5 ml of aflatoxin B1 + 80 grams of yeast; T4, addition of 0.5 ml of aflatoxin B1 + 1 ml of vitamin E; T5, addition of 0.5 ml of aflatoxin B1 + 40 grams of zeolite; and T6, addition of 0.5 ml of aflatoxin B1 + 80 grams of yeast + 1 ml of vitamin E + 40 grams of zeolite.
The results showed a significant increase (P≤0.05) in the weight of both the testes and the prostate when comparing the different treatments to the control group (T1). However, a noticeable decrease in weight was observed in the group exposed to aflatoxin B1 (T2). Additionally, a significant increase (P≤0.01) in FSH levels was found in (T2) compared to (T1) and (T6). A significant decrease (P≤0.01) in LH and testosterone levels was observed in (T2) compared to (T1). Histological analysis revealed tissue damage in the testes, including significant degeneration of the seminiferous tubules, absence of spermatogenic cells, and lack of mature spermatozoa, as well as an increase in the number of deformed spermatozoa due to the toxic effects of aflatoxin B1. Therefore, the study provides significant insights into the impact of aflatoxin B1 and various bio adsorbents on the male reproductive system in rats.
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